PT - JOURNAL ARTICLE AU - P Amami AU - I Dekker AU - S Piacentini AU - F Ferré AU - L M Romito AU - A Franzini AU - E M J Foncke AU - A Albanese TI - Impulse control behaviours in patients with Parkinson's disease after subthalamic deep brain stimulation: de novo cases and 3-year follow-up AID - 10.1136/jnnp-2013-307214 DP - 2015 May 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 562--564 VI - 86 IP - 5 4099 - http://jnnp.bmj.com/content/86/5/562.short 4100 - http://jnnp.bmj.com/content/86/5/562.full SO - J Neurol Neurosurg Psychiatry2015 May 01; 86 AB - Objective To document the occurrence of impulse control behaviours (ICBs) in patients with Parkinson's disease after 3 years of continuous deep brain stimulation (DBS) of the subthalamic nucleus (STN). Methods Detailed neurological and ICB assessments were performed before STN DBS and up to 3 years after implant. Results 13 out of 56 patients (23.2%) had ICBs at baseline; they took higher doses of dopamine agonists (DAA). Three years after implant 11 had fully remitted with a 60.8% reduction of DAA medication; the remaining two, who had a similar medication reduction, had only compulsive eating, having recovered from hypersexuality. Six of the 43 patients without ICBs at baseline (14%) developed transient de novo ICBs after implant; none of them had ICBs at the 3-year observation. Conclusions ICBs were abolished in patients 3 years after STN DBS and DAA dosages were lowered. New ICBs may occur after implant and are transient in most cases. Compulsive eating may be specifically related to STN stimulation.