RT Journal Article SR Electronic T1 ANALYSIS OF AN ADULT DUCHENNE MUSCULAR DYSTROPHY POPULATION: TEN YEARS ON JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP e4 OP e4 DO 10.1136/jnnp-2015-312379.149 VO 86 IS 11 A1 Kit Wu A1 Axelle Rigaudy A1 Loucas Christodoulou A1 Aren Okello A1 Emily Ballard A1 Nicholas Hart A1 Robin Howard YR 2015 UL http://jnnp.bmj.com/content/86/11/e4.56.abstract AB Background Duchenne muscular dystrophy (DMD) is a progressive, multi-systemic condition, management of which has benefitted from improvements in research and healthcare.Aim 1. To review the multidisciplinary management of a late adolescent and adult DMD population attending the Lane Fox Respiratory Unit. 2. To compare the findings to those of an audit conducted 10 years previously (Parker et al, QJM. 2005.), so to identify areas of improvement and issues that require further input.Method We studied 30 patients with DMD referred to an adult neuromusclular clinic over a ten-year period. Clinical details were obtained from case notes or direct observations.Results The age for our cohort ranged from 19 to 49 years, all of whom became symptomatic before ten years old. Nine patients died during the study period. 25 patients were wheelchair bound in their mid-teens. Over the last ten years, areas of improvement include provision of non-invasive ventilation, provision of aids, and access to education (9/30 of our cohort attended university or college, and three patients are in active employment). Areas of care that need further input are management of mood, bowel hygiene, fatigue and pain.Discussion Despite improvements in several areas, there is still a need for a consistent and multi-faceted approach to management of DMD.