PT - JOURNAL ARTICLE AU - Gallardo, Elena AU - Noto, Yu-ichi AU - Simon, Neil G TI - Ultrasound in the diagnosis of peripheral neuropathy: structure meets function in the neuromuscular clinic AID - 10.1136/jnnp-2014-309599 DP - 2015 Oct 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 1066--1074 VI - 86 IP - 10 4099 - http://jnnp.bmj.com/content/86/10/1066.short 4100 - http://jnnp.bmj.com/content/86/10/1066.full SO - J Neurol Neurosurg Psychiatry2015 Oct 01; 86 AB - Peripheral nerve ultrasound (US) has emerged as a promising technique for the diagnosis of peripheral nerve disorders. While most experience with US has been reported in the context of nerve entrapment syndromes, the role of US in the diagnosis of peripheral neuropathy (PN) has recently been explored. Distinctive US findings have been reported in patients with hereditary, immune-mediated, infectious and axonal PN; US may add complementary information to neurophysiological studies in the diagnostic work-up of PN. This review describes the characteristic US findings in PN reported to date and a classification of abnormal nerve US patterns in PN is proposed. Closer scrutiny of nerve abnormalities beyond assessment of nerve calibre may allow for more accurate diagnostic classification of PN, as well as contribute to the understanding of the intersection of structure and function in PN.