PT  - JOURNAL ARTICLE
AU  - Faiza Khan Afridi
AU  - Jamil Ahmed Malik
AU  - Muhammad Sajjad Khan
TI  - I23 Relationship between stress and quality of life in students at risk of huntington’s disease: changing patterns of social support across age
AID  - 10.1136/jnnp-2016-314597.188
DP  - 2016 Sep 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - A66--A67
VI  - 87
IP  - Suppl 1
4099  - http://jnnp.bmj.com/content/87/Suppl_1/A66.3.short
4100  - http://jnnp.bmj.com/content/87/Suppl_1/A66.3.full
SO  - J Neurol Neurosurg Psychiatry2016 Sep 01; 87
AB  - Background Being at risk for development of Huntington’s disease due to genetic influence evokes stress among adolescent and young adults resulting in poor quality of life. Social support is assumed as cushion to decrease negative consequences of stress associated with risk. Aims The study is aimed to investigate the role of social support across various stages of development. We assume that social support may have a varying role across various age groups for the relationship between stress and quality of life.Method Participants were identified using referrals and approached at their homes. Inclusion criteria were students at risk of developing Huntington due to genetic influence. A total of N = 30 participants with age ranging from 14–27 years with Mean ± SD (20.97 ± 3.25) including 63% females were approached. Along with demographic information, participants were asked to respond on Social Support Questionnaire, Depression, Anxiety, and Stress Scale (DASS), and WHO-QOL (BREF).Results Preliminary analysis showed that social support significantly negatively correlated with stress (r = −0.47, P < 0.01) and positively correlated with qol (r = 0.48, p < 0.01). Processes macro was used to conduct a moderated moderation for testing varying effect of social support on the relationship between stress and qol across age resulting in a significant 3-way interaction (B = 0.11, p < 0.05: ΔR2 = 0.10). Modgraph showed an inverse role of social support for adolescent versus adults. Low social support is beneficial for adolescents and high social support is beneficial for adults. Conclusions High social support to adolescents has negative consequences on those who might be struggling with autonomy and independence from elders.