%0 Journal Article %A Francesca Puledda %A Lau Tze %A Christoph Schankin %A Peter Goadsby %T PO070 Treatment effect in visual snow %D 2017 %R 10.1136/jnnp-2017-ABN.102 %J Journal of Neurology, Neurosurgery & Psychiatry %P A30-A30 %V 88 %N Suppl 1 %X Patients with visual snow suffer from pan-field, dynamic visual disturbance. Proposed diagnostic criteria require at least two additional visual symptoms from: palinopsia, entoptic phenomena, photophobia and nyctalopia. Little is known regarding useful pharmacological treatments for patients. The aim of this study was to gain knowledge on the effect of a number of commonly used medications on visual snow. A questionnaire was prepared in collaboration with the patient group Eye-on-Vision and sent to subjects who had expressed an interest in research. It required to select from a list of drugs, including antiepileptics, antidepressants and benzodiazepines, the treatments that caused a change in symptoms, with either an improvement or a worsening. The study was approved by KCL Research Ethics Panel. For a total of n=182 patients, the effect of ninety-six drugs was recorded in 514 reports. Antidepressants and antiepileptics were the most commonly used drugs; they showed no effect on visual snow in 53% of reports. Visual snow is a highly disabling syndrome, for which there is no widely accepted treatment. More effort needs to be made in understanding its pathophysiology to allow focused treatment strategies. %U https://jnnp.bmj.com/content/jnnp/88/Suppl_1/A30.2.full.pdf