TY - JOUR T1 - Meaning of psychiatric symptoms in frontotemporal dementia JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry DO - 10.1136/jnnp-2017-317556 SP - jnnp-2017-317556 AU - Yolande A L Pijnenburg AU - Annemiek Dols Y1 - 2018/02/08 UR - http://jnnp.bmj.com/content/early/2018/02/07/jnnp-2017-317556.abstract N2 - Cheran et al1 in this journal investigated the nature of lifetime psychiatric symptoms in preclinical MAPT mutation carriers. Compared with their non-carrier relatives as well as the population, they more often had signs of atypical depression, not fulfilling the criteria of major depressive disorder, and they did not have the anxiety and mood disorders that characterised their non-carrier controls. Since atypical depression was a current condition, and no other psychiatric disturbances were reported from their earlier lifespan, some form of emotional blunting and a relative absence of fear might be among the prodromes or early beginning of behavioural variant frontotemporal dementia (bvFTD).Defining the onset of bvFTD in persons … ER -