PT  - JOURNAL ARTICLE
AU  - H Asif
AU  - C Craven
AU  - L Thorne
AU  - L Watkins
AU  - A Toma
TI  - TM3-5 Venous sinus stenting for IIH: what are the long-term outcomes?
AID  - 10.1136/jnnp-2019-ABN.51
DP  - 2019 Mar 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - e16--e16
VI  - 90
IP  - 3
4099  - http://jnnp.bmj.com/content/90/3/e16.2.short
4100  - http://jnnp.bmj.com/content/90/3/e16.2.full
SO  - J Neurol Neurosurg Psychiatry2019 Mar 01; 90
AB  - Objectives Idiopathic intracranial hypertension (IIH) is associated with dural venous sinus stenosis (DVSS). This is increasingly treated with endovascular insertion of stents. Clinical and manometric improvements after stent placement have been described. However, there is little data reporting further need for CSF diversion, complication rates and sustained improvements in ICP.Design Single centre case series.Subjects Twenty-four IIH patients underwent stent insertion on discovery of DVSS with medical management ongoing.Methods Clinical notes, radiographic reports and 24 hour ICP monitoring data before and after stent placement was collected.Results After 1089.2±107.1 days, 6 patients remained symptomatic and went onto require CSF diversion, 75.0% did not require CSF diversion. One patient developed stent thrombosis requiring VKA anticoagulation for 3 months, this patient also developed new stenosis proximal to the stent at 2 years. A second patient developed in-stent stenosis requiring balloon angioplasty at 2 years and subsequent repeat stenting at 3 years. Eleven patients had 24 hour ICP monitoring at baseline and a mean of 231.9±129.5 days after DVSS stent placement. The mean reduction in ICP was 7.92±1.80 mmHg (p<0.01) and PA was 2.84±0.84 mmHg (p<0.01).Conclusions DVSS stenting is a viable endovascular therapy for IIH with modest long-term patency and ICP reduction. However, a quarter of stented patients required subsequent CSF diversion to manage their symptoms.