RT Journal Article
SR Electronic
T1 Seizures and movement disorders: phenomenology, diagnostic challenges and therapeutic approaches
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 920
OP 928
DO 10.1136/jnnp-2018-320039
VO 90
IS 8
A1 Maria Eliza Freitas
A1 Marta Ruiz-Lopez
A1 Josep Dalmau
A1 Roberto Erro
A1 Michael Privitera
A1 Danielle Andrade
A1 Alfonso Fasano
YR 2019
UL http://jnnp.bmj.com/content/90/8/920.abstract
AB Seizures and movement disorders (MDs) are distinct neurological conditions presenting with abnormal movements. Despite sharing an overlap in phenomenology, these movements have different origins. In order to explore the overlaps and the narrow boundaries between these two conditions, we performed a review of the literature to explore the risk of seizures in MDs. We discussed the mimics and chameleons including MDs that look like seizure (eg, paroxysmal dyskinesia, status dystonicus) and seizures that look like MDs (eg, epilepsia partialis continua, nocturnal frontal lobe epilepsy). Additionally, we examined the therapeutic challenges as well as the anatomical and chemical pathways relevant in the interplay between epilepsy and MDs. Finally, we proposed an algorithm to guide clinicians towards the final diagnosis of conditions characterised by the co-occurrence of MDs and seizures.