PT  - JOURNAL ARTICLE
AU  - Esther Boot
AU  - Merel Sanne Ekker
AU  - Jukka Putaala
AU  - Steven Kittner
AU  - Frank-Erik De Leeuw
AU  - Anil M Tuladhar
TI  - Ischaemic stroke in young adults: a global perspective
AID  - 10.1136/jnnp-2019-322424
DP  - 2020 Apr 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 411--417
VI  - 91
IP  - 4
4099  - http://jnnp.bmj.com/content/91/4/411.short
4100  - http://jnnp.bmj.com/content/91/4/411.full
SO  - J Neurol Neurosurg Psychiatry2020 Apr 01; 91
AB  - Ischaemic stroke at young age is an increasing problem in both developing and developed countries due to rising incidence, high morbidity and mortality and long-term psychological, physical and social consequences. Compared with stroke in older adults, stroke in young adults is more heterogeneous due to the wide variety of possible underlying risk factors and aetiologies. In this review, we will provide an overview of the global variation in the epidemiology of stroke in young adults, with special attention to differences in geography, ethnicity/race and sex, as well as traditional and novel risk factors for early-onset ischaemic stroke, such as air pollution. Understanding global differences is an important prerequisite for better region-specific prevention and treatment of this devastating condition.