Table 5

ApoE alleles in non-demented 85 year old people in relation to the incidence of dementia per 1000 person-years at risk between age 85 and 88

Subjects (n)OR for dementia disorders in those having at least one allele of:
ε2 v no ε2ε3 v no ε3ε4 v no ε4
No dementia223
Any dementia591.2  (0.6  to   2.2)1.7  (0.4  to    7.1)1.2  (0.7  to   2.1)
Alzheimer’s disease (AD)240.3 (0.1  to   1.4)1.4 (0.2  to   10.6)2.1(0.9  to   4.8)
Mixed dementia (MIX)3
Multi-infarct dementia (MID)242.95-150 (1.3  to   6.6)1.4 (0.2  to   10.4)0.7 (0.3  to   1.6)
Other dementias70.6 (0.1  to   4.9)3.8 (0.7  to   20.0)
All AD (including MIX)270.3 (0.1  to   1.2)1.6 (0.2  to   11.9)1.6 (0.7  to   3.5)
All vascular dementia (MID+MIX+hypoperfusion)282.55-150 (1.2  to   5.5)1.6 (0.2  to   12.2)0.5 (0.2  to   1.3)
  • 5-150 p < 0.05; p < 0.10 v people without the allele.

  • — Not calculated because of small groups.