ApoE alleles in non-demented 85 year old people in relation to the incidence of dementia per 1000 person-years at risk between age 85 and 88
| Subjects (n) | OR for dementia disorders in those having at least one allele of: | ||||
|---|---|---|---|---|---|
| ε2 v no ε2 | ε3 v no ε3 | ε4 v no ε4 | |||
| No dementia | 223 | ||||
| Any dementia | 59 | 1.2 (0.6 to 2.2) | 1.7 (0.4 to 7.1) | 1.2 (0.7 to 2.1) | |
| Alzheimer’s disease (AD) | 24 | 0.3 (0.1 to 1.4) | 1.4 (0.2 to 10.6) | 2.1†(0.9 to 4.8) | |
| Mixed dementia (MIX) | 3 | — | — | — | |
| Multi-infarct dementia (MID) | 24 | 2.95-150 (1.3 to 6.6) | 1.4 (0.2 to 10.4) | 0.7 (0.3 to 1.6) | |
| Other dementias | 7 | 0.6 (0.1 to 4.9) | — | 3.8 (0.7 to 20.0) | |
| All AD (including MIX) | 27 | 0.3† (0.1 to 1.2) | 1.6 (0.2 to 11.9) | 1.6 (0.7 to 3.5) | |
| All vascular dementia (MID+MIX+hypoperfusion) | 28 | 2.55-150 (1.2 to 5.5) | 1.6 (0.2 to 12.2) | 0.5 (0.2 to 1.3) | |
↵5-150 p < 0.05; † p < 0.10 v people without the allele.
— Not calculated because of small groups.