Table 1

Clinical data on patients (only the major interictal paroxysmal EEG changes are shown)

PatientAge at seizure onsetAge at PET (y)Syndrome diagnosisSeizure typesInterictal EEG
16 months10LGS after ISIS, DA, M, GTCSHyps, SSW, MSW
26 months5LGS after ISIS, M, THyps, SSW, MSW
36 months10LGS after ISIS, GTCS, A, T, AtA, M Hyps, SSW, FR
48 months12LGS after ISIS, T, AtASSW
52 months11 *LGS after ISIS, AtA, T, GTCS, MHyps, SSW, MSW
63 months7 *LGS after ISC, IS, T, M, M-AMSW
73 weeks9 *LGS after ISNeoS, IS, T, GTCSHyps, SSW
83 y11De novo LGSAtA, A, NCSSSW
92 y8De novo LGSGTCS, A, T, M, CSSSW
105 y8De novo LGSGTCS, A, AtA, TSSW
113 y9De novo LGSGTCS, A, T, AtA, M SSW, FR
124 y12De novo LGSGTCS, A, AtA, T, NCSSSW, MSW
133 y9 *De novo LGST, A, AtA, USSW, FR
143 y5 *De novo LGSGTCS, AtA, USSW, MSW
151 y5 *De novo LGSC, GTCS, A, M, T, AtASSW, FR
163 y10 *De novo LGSA, C, T, AtA, NCSSSW, MSW
172 months10SMEIC, GTCS, M-A, AtA, T, CSSW, MSW
185 months6SMEIC, GTCS, M, AtASW, MSW
195 months11SMEICS, GTCS, AtA, T, MSW
207 months12SMEICS, GTCS, AtA, CP, M, T SW, MSW
213 months3SMEICS, GTCS, AtA, MDiffuse slow only
225 months11SMEIGTCS, M, AtA, CSW, MSW, PCR
2315 months4 *SMEIGTCS, AtA, MSW
2412 months10 *SMEIM, GTCS, AtA, TMSW
2511 months12 *EM-ASM, M-A, Ab, GTCS, T, NCSSW
262 y11 *EM-ASM, GTCS, M-A, Ab, NCSSW, MSW, PCR
277 y12UnclassifiedU, T, AtASSW, MSW
282 y5UnclassifiedGTCS, NCS, CS, M, T, AtASSW, MSW
291 y2UnclassifiedU, AtA, MA, MMSW
301 y8UnclassifiedAtA, DA, T, M, CSW, MSW, PCR
319 months6UnclassifiedGTCS, M, AtA, TMSW
325 months5UnclassifiedGTCS, TMSW
  • IS = infantile spasms; LGS = Lennox-Gastaut syndrome; SMEI = severe mtoclonic epilepsy in infancy; EM-AS = epilepsy with myoclonic-astatic seizures; DA = drop attacks (type undetermined); M = myoclonic; GTCS = generalised tonic-clonic seizures; T = tonic; A = atonic; AtA = atypical absence; M-A = myoatonic; NeoS = neonatal seizure; NCS = non-convulsive status; CS = convulsive status; C = clonic; Ab = absence; Hyps = hypsarrythmia; SSW = slow spike and wave; MSW = multiple spike and wave; FR = fast rhythms in sleep; PCR = photoconvulsive response; * certain features in these patients were considered atypical of the syndrome (Ferrie et al 11); implies seizure type was rare; no EEG performed during period of active spasms.