Table 2

Ratio of FDG uptake in patients and historical age matched controls in cortical regions and subcortical structures compared with cerebellar uptake

Age (y)ControlsWhole groupNo focal abnormalities on PETFocal abnormalities on PET
Frontal cortex:
 1-2 (n=4)1.52 (0.27)
 3-8 (n=12)1.67 (0.10)1.37 (0.30)2-150 1.28 (0.20)1.50 (0.30)
 9-15 (n=6)1.63 (0.07)1.36 (0.34)2-150 1.50 (0.36)1.24 (0.31)
 19-30 (n=7)
Parietal cortex:
 1-21.47 (0.26)
 3-81.67 (0.10)1.14 (0.26)** 1.07 (0.16)1.25 (0.32)
 9-151.57 (0.07)1.14 (0.32)2-150 1.27 (0.39)1.04 (0.22)
 19-30
Occipital cortex:
 1-21.67 (0.28)
 3-81.75 (0.11)1.18 (0.23)** 1.08 (0.24)1.28 (0.20)
 9-151.67 (0.05)1.25 (0.20)** 1.23 (0.23)1.22 (0.19)
 19-30
Temporal cortex:
 1-21.56 (0.27)
 3-81.52 (0.09)1.07 (0.27)** 0.99 (0.19)1.16 (0.35)
 9-151.46 (0.06)1.01 (0.26)** 1.12 (0.25)0.92 (0.24)
 19-30
Lentiform nuclei:
 1-21.66 (0.30)
 3-81.64 (0.10)1.56 (0.23)1.48 (0.12)1.64 (0.31)
 9-151.76 (0.06)1.61 (0.25)1.74 (0.24)1.51 (0.20)
 19-301.78 (0.10)
Caudate nuclei:
 1-21.48 (0.30)
 3-81.51 (0.10)1.43 (0.24)1.30 (0.14)1.57 (0.27)
 9-151.63 (0.05)1.42 (0.22)1.55 (0.17)1.32 (0.20)
 19-301.71 (0.10)
Thalami:
 1-21.51 (0.25)
 3-81.53 (0.09)1.21 (0.25)*** 1.11 (0.10)1.32 (0.33)
 9-151.60 (0.05)1.26 (0.21)*** 1.34 (0.24)1.18 (0.17)
 19-301.71 (0.13)
  • 2-150 P < 0.005; ** P < 0.0028; *** P < 0.001.

  • The SDs for the control values were calculated by the delta method22. Only one patient (data not shown) was aged 2 to 3 years. Control values for subcortical structures in subjects aged 19-30 years are included as reference is made to them in the discussion.