Table 1

Clinical characteristics of the patients

Patient No		Sex		Cutaneous angioma		Seizures before SPECT (age at 1st seizure)		Characteristics at the time of SPECT examination		Follow up
Patient No		Sex		Cutaneous angioma		Seizures before SPECT (age at 1st seizure)		Age	CT signs	Follow up	MRI signs	AED	Neurological examination	Mental development
1	M	Left	No	8 days	None	WMH	None		Normal	2 y
			No	10 m		None	PB	Normal	Normal
2	M	Left	No	15 days	PH	WMH, PH^1-150	None	Normal	Normal	1 y
			No	10 m		A, PH	PB	R hemianopsia	Normal
3	F	Left	No (14 m)	17 days	None	WMH	None	Normal	Normal	1.5 y
			No (14 m)	11 m		None	PB	Normal	Normal
4	F	Right	No (3 m)	1 m		None	PB	Normal	Normal	2 y
5	M	Left	No (6 m)	1 m	PH		PB	Normal	Mildly delayed	6 y
			Yes (6 m)	10 m	PH, A, CE	A	PB	Normal	Normal	6 y
6	M	Right	No	1 m	A	A, PH, WMH	PB	Normal	Normal	6 m
7	M	Right	No	1 m	PH	WMH	None	Normal	Normal	2 y
			No	6 m			PB	Normal	Normal
8	M	Left	No	1.5 m	None	None	PB	Normal	Normal	1 y
9	F	Left	No (23 m)	1.5 m	None	None	PB	Normal	Normal	2 y
10	F	Right	No (3 m)	2 m	PH	WMH	PB	Normal	Normal	2 y
			Yes (3 m)	7 m		A	CBZ	Normal	Normal
11	M	Left	No (7 m)	3.5 m	PH		None	Normal	Normal	5 y
			Yes (7 m)	7.5 m	PH		PB	R hemiparesis	Normal	7 y
12	M	Right	No	12 m	A	A	PB	Normal	Normal	5 y
13	F	Bilateral	Yes (7 days)	2 m	A, PH	A, WMH	PB	Hypotonia	Severely delayed	4 y
14	F	Right	Yes (1 day)	2.5 m	A, CE		PB	Normal	Mildly delayed	7 y
15	M	Left	Yes (3 m)	3.5 m	A, CE, PH		PB, CZP	R hemiplegia	Normal	1.5 y
16	F	Left	Yes (9 m)	9 m	None		CBZ, CLB	R hemiparesis	Speech delayed	7 y
17	F	Left	Yes (6 m)	9 m	None	CE, WMH	VPA		Normal	5 y
18	M	Left	Yes (4 m)	11 m	CE, C		PB	R hemiplegia	Mildly delayed	3 y
19	M	None	Yes (3 weeks)	13 m	A, C		PB	L hemiparesis	Speech delayed	7 y
20	M	Right	Yes (3 m)	15 m	A, CE	A, CE, WMH	CBZ, CZP	L hemiplegia	Severely delayyed	1.5 y
21	M	Left	Yes (13 m)	17 m	OE		CBZ	Normal	Mildly delayed	8 y
22	M	Left	Yes (11 m)	24 m	A, CE	A	CBZ	Normal	Speech delayed	2 y

↵1-150 Injection of gadolinium performed.
m = months; y = years; PH = choroid plexus hypertrophy; A = atrophy; CE = contrast enhancement; C = calcifications; WMH = white matter hypersignal; AED = antiepileptic drugs; PB = phenobarbitone; CBZ = carbamazepine; CLB = clobazam; CZP = clonazepam.