Amyotrophic lateral sclerosis phenotypes. Overall and men versus women mean annual crude incidence rates (/100 000 population), 95% CIs and gender incidence rate ratios
| Phenotype | Overall, incidence rate (95% CI) | Men, incidence rate (95% CI) | Women, incidence rate (95% CI) | Men to women incidence rate ratio |
| Classic | 0.94 (0.85 to 1.04) | 1.17 (1.03 to 1.32) | 0.71 (0.61 to 0.83) | 1.65:1 |
| Bulbar | 1.05 (0.96 to 1.15) | 1.04 (0.91 to 1.19) | 1.06 (0.94 to 1.20) | 0.98:1 |
| Flail arm | 0.17 (0.13 to 0.21) | 0.28 (0.21 to 0.36) | 0.07 (0.04 to 0.12) | 4.00:1 |
| Flail leg | 0.40 (0.34 to 0.47) | 0.40 (0.32 to 0.50) | 0.39 (0.31 to 0.48) | 1.03:1 |
| Pyramidal | 0.28 (0.23 to 0.34) | 0.28 (0.21 to 0.36) | 0.27 (0.21 to 0.35) | 1.04:1 |
| Respiratory | 0.03 (0.02 to 0.05) | 0.06 (0.03 to 0.10) | 0.01 (0 to 0.03) | 6.00:1 |
| PLMN | 0.08 (0.06 to 0.11) | 0.11 (0.07 to 0.17) | 0.05 (0.03 to 0.08) | 2.04:1 |
| PUMN | 0.12 (0.09 to 0.16) | 0.12 (0.08 to 0.18) | 0.12 (0.08 to 0.17) | 0.98:1 |
| Overall ALS | 3.07 (2.89 to 3.25) | 3.46 (3.23 to 3.71) | 2.68 (2.44 to 2.90) | 1.29:1 |
ALS, amyotrophic lateral sclerosis; PLMN, pure lower motor neuron phenotype; PUMN, pure upper motor neuron phenotype.