Table 1

Clinical details of families A and B

Case	Age	HSP onset	Clinical features	Other features
IV-2A	39	17	All members have macular pigmentation (except IV-3B), mental retardation, dementia, distal amyotrophy, mild cerebellar signs, and bladder and bowel incontinence		Psychosis
IV-5A	33	18			Psychosis
IV-6A	32	23			Nil
IV-1B	33	13			Epilepsy
IV-2B	32	14			Nil
IV-3B	30	16			Dystonia

HSP=Hereditary spastic paraplegia.