Neuronal densities in hippocampal subregions
| Hippocampal subregion | Controls (n=6) | Hippocampal sclerosis with corpora amylacea (n=26) | Hippocampal sclerosis without corpora amylacea (n=15) |
|---|---|---|---|
| CA1 | 20.3 (15.6–23.4) | 2.6 (1.2–8.9) | 2.8 (1.7–9.6) |
| CA2 | 30.2 (25.7–38.0) | 20.0 (12.3–28.1) (n=17) | 20.2 (14.8–30.4) (n=7) |
| CA3 | 16.4 (15.6–25.9) | 4.9 (1.1–16.5) (n=16) | 7.9 (3.8–8.4) (n=7) |
| Hilus | 12.0 (8.6–14.9) | 2.7 (0.9–8.6) | 1.5 (0.6–9.6) |
| GCDG | 482 (295–635) | 180 (80–490) (n=25) | 152 (41–270) (n=14) |
Neuronal densities of five hippocampal subregions for control, hippocampal sclerosis with corpora amylacea and hippocampal sclerosis without corpora amylacea specimens; n=number of specimens for which a particular hippocampal subregion was available for counting studies. In the other specimens, these regions were damaged during surgical removal and therefore not available for quantitative neuropathological studies. In two hippocampal sclerosis specimens, the GCDG was almost completely destroyed and technically difficult to count. Neuronal densities are number of cells × 103/mm3. Neuronal density is expressed as median (range). The neuronal densities of hippocampal sclerosis specimens with and without corpora amylacea are comparable.