Table 1

Paraneoplastic neurological syndromes in small cell lung cancer

Unifocal syndromes:
 Lambert-Eaton myasthenic syndrome (LEMS)
Paraneoplastic cerebellar degeneration (PCD) 1-150
Paraneoplastic sensory neuronopathy (PSN) 1-150
Limbic encephalopathy 1-150
Opsoclonus-myoclonus 1-150
Paraneoplastic visual symptoms
 Cancer associated retinopathy
 Optic neuritis
Motor neuron syndrome1-150, lower motor neuron or both upper and lower motor neuron
Neuromyotonia
Myotonia
Vasculitis of the nerve and muscle
Multifocal syndromes:
Paraneoplastic encephalomyelitis (PEM) and PSN
PEM and optic neuritis
PEM and vasculitis of the nerve and muscle
Overlapping syndromes:1-151
LEMS and PCD
LEMS and PEM
  • 1-150 They may evolve to PEM or remain isolated.

  • 1-151 Independent pathogenic mechanisms.