Case No and authors | Age (y) /sex | Clinical diagnosis | Codon 1291-150 | Brain weight (g) | Spongiform change | Kuru type amyloid plaques | Distribution of the lesions | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cerebral cortex | Deep grey matter | White matter | Cerebellum | ||||||||||||
1 Miyashita et al 5 | 26/F | CJD | NE | 920 | + | + | + | + | |||||||
2 Willison et al 6 | 30/M | CJD | NE | + | + | + | + | ||||||||
3 Pocchiari et al 7 | 32/F | CJD | Val/Val | 950 | + | + | + | ||||||||
4 Esmonde et al,8 case 2 | 44/F | CJD | NE | + | − | + | + | + | |||||||
5 Lane et al 9 | 28/F | Idiopathic cerebellar degeneration | NE | 1200 | + | + | + | + | + | + | |||||
6 Yamadaet al 10 | 31/F | CJD | Met/Met | 750 | + | − | + | + | + | + | |||||
7 This case | 52/M | CJD | Met/Met | 760 | + | − | + | + | +1-151 | + |