Comparison of the three groups: non-carriers (NC), paired associates unimpaired (PAU), and impaired (PAI) carriers (mean (SD))
| Non-carriers | Carriers PAU | Significance NC v | Significance carriers PAI v | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Carriers PAU | Carriers PAI | Non-carriers | Carriers PAU | ||||||||
| Number | 49 | 32 | 10 | ||||||||
| MMS | 29.6 (0.6) | 29.7 (0.6) | NS | 29.3 (0.9) | NS | NS | |||||
| MATTIS DRS | 142.5 (2.6) | 143.0 (1.5) | NS1-150 | 138.6 (4.9) | 0.0091-150 | 0.0041-150 | |||||
| Serial sevens | 4.7 (0.8) | 4.7 (0.5) | NS | 4.4 (1.3) | NS | NS | |||||
| Digit span direct | 6.5 (1.1) | 6.7 (1.2) | NS | 6.3 (1.1) | NS | NS | |||||
| Digit span reverse | 4.7 (1.0) | 4.7 (1.0) | NS | 4.7 (1.2) | NS | NS | |||||
| Stroop test words | 99.6 (4.9) | 99.5 (3.0) | NS | 95.6 (10.0) | NS | NS | |||||
| Stroop test colours | 80.6 (10.8) | 80.5 (11.1) | NS | 75.8 (13.2) | NS | NS | |||||
| Stroop test interference | 49.7 (10.3) | 50.5 (9.8) | NS | 45.1 (9.3) | NS | NS | |||||
| Trail making A | 32.7 (9.4) | 29.5 (10.9) | NS | 34.5 (7.4) | NS | NS | |||||
| Trail making B | 68.9 (26.6) | 65.8 (29.2) | NS | 102.9 (55.2) | NS | NS | |||||
| Trail making test B−A | 36.2 (23.0) | 37.4 (23.8) | NS | 69.4 (52.8) | NS | NS | |||||
| Arithmetic | 10.7 (3.4) | 10.4 (3.2) | NS | 6.1 (3.2) | 0.0002 | 0.0006 | |||||
| Digit symbol | 11.2 (2.6) | 11.2 (2.7) | NS | 8.8 (1.5) | 0.007 | 0.01 | |||||
| Verbal fluency | 21.5 (1.8) | 22.8 (5.8) | NS | 16.2 (4.2) | NS | 0.001 | |||||
| WMS - memory quotient | 113.2 (7.4) | 112.6 (6.9) | NS | 98.7 (7.6) | 0.0001 | 0.0002 | |||||
| WMS - logical memory | 13.5 (3.1) | 13.1 (3.0) | NS | 8.7 (2.7) | 0.0001 | 0.0002 | |||||
| WMS - paired associates | 19.5 (2.0) | 19.8 (1.3) | NS | 14.6 (1.9) | 0.0001 | 0.0001 | |||||
| WMS - hard paired associates | 10.9 (0.8) | 11.0 (1.1) | NS | 6.2 (1.7) | 0.0001 | 0.0001 | |||||
| WMS - visual retention | 13.6 (2.0) | 13.3 (2.4) | NS | 12.2 (2.4) | NS | NS | |||||
| WMS - delayed logical memory | 13.4 (3.1) | 12.5 (2.8) | NS1-150 | 8.0 (2.9) | 0.00011-150 | 0.00041-150 | |||||
| WMS - delayed paired associates | 6.9 (0.3) | 6.9 (0.2) | NS | 6.6 (0.5) | NS | 0.007 | |||||
| WMS - delayed visual retention | 13.2 (2.5) | 12.8 (3.3) | NS | 10.6 (3.7) | 0.008 | NS | |||||
| CVLT - monday list - trial 1 | 9.1 (2.3) | 8.9 (5.1) | NS | 6.9 (1.2) | 0.004 | 0.009 | |||||
| CVLT - monday list - trial 5 | 14.9 (1.2) | 14.7 (1.5) | NS | 13.2 (0.9) | 0.0002 | 0.006 | |||||
| CVLT - total 5 trials | 63.8 (7.0) | 63.9 (7.5) | NS | 53.7 (6.1) | 0.0001 | 0.0003 | |||||
| CVLT - tuesday list | 9.0 (2.1) | 9.8 (2.4) | NS | 7.7 (1.4) | NS | NS | |||||
| CVLT - short delay free recall | 13.8 (1.5) | 13.7 (2.2) | NS | 11.6 (1.9) | 0.0001 | 0.009 | |||||
| CVLT - short delay cued recall | 14.5 (1.3) | 14.6 (1.5) | NS | 11.4 (2.1) | 0.0001 | 0.0001 | |||||
| CVLT - long delay free recall | 14.4 (1.4) | 14.3 (1.8) | NS | 11.2 (1.9) | 0.0001 | 0.0001 | |||||
| CVLT - long delay cued recall | 14.8 (1.1) | 14.8 (1.3) | NS | 11.9 (2.2) | 0.0001 | 0.0001 | |||||
| CVLT - correct recognitions | 15.8 (0.4) | 15.6 (0.7) | NS1-150 | 14.3 (1.3) | 0.00011-150 | 0.0011-150 | |||||
| CVLT - total intrusions | 2.8 (1.5) | 3.1 (1.6) | NS1-150 | 4.6 (2.1) | NS1-150 | NS1-150 | |||||
| CVLT - total perseverations | 4.2 (1.9) | 4.7 (2.1) | NS1-150 | 6.2 (2.2) | 0.0091-150 | NS1-150 | |||||
| CVLT - total false alarms | 1.3 (0.7) | 1.6 (1.0) | NS1-150 | 1.9 (1.3) | NS1-150 | NS1-150 | |||||
| CVLT - discriminability | 99.1 (1.8) | 97.9 (2.8) | NS1-150 | 94.1 (5.3) | 0.00031-150 | 0.011-150 | |||||
| CVLT - consistency | 90.2 (7.6) | 91.6 (6.4) | NS1-150 | 82.1 (7.0) | 0.0021-150 | 0.00081-150 | |||||
| CVLT - semantic clustering | 2.7 (1.1) | 2.8 (1.0) | NS | 1.6 (0.8) | 0.001 | 0.001 | |||||
| CVLT - serial clustering | 1.6 (1.7) | 1.7 (1.8) | NS | 2.7 (1.7) | NS | NS | |||||
↵1-150 Mann-Whitney U test (z test scores corrected for ties). Otherwise, unpaired Student’s ttest. NS = p>0.01.