Clinical and cognitive comparisons of late hallucinators and non-hallucinators
| Late hallucinators (n=13) | Late Non-hallucinators (n=42) | Statistic | |
|---|---|---|---|
| Mean (SD) | Mean (SD) | t Value | |
| Age at onset (y) | 52.0 (10.7) | 50.0 (9.5) | 0.62 |
| Nart IQ | 108.3 (6.1) (n=11) | 110.9 (8.7) | 0.95 |
| Dose levodopa (mg) | 614 (433) (n=14) | 667mg (286) (n=35) | 0.50 |
| Dose DA agonist (mg) | 3.06 (1.76) (n=11) | 3.11mg (1.85) (n=18) | 0.07 |
| Number of drugs | 2.0 (0.82) | 1.83 (0.70) | 0.72 |
| UPDRS ADL | 23.2 (7.4) | 17.8 (8.2) | 2.03 |
| UPDRS motor | 32.3 (14.5) | 26.1 (12.2) | 1.48 |
| AFT right | 77.1 (48.3) (n=8) | 73.6 (31.0) (n=30) | 0.25 |
| AFT left | 64.6 (43.7) (n=8) | 69.4 (23.0) (n=29) | 0.30 |
| BDI | 8.4 (2.9) (n=11) | 13.0 (7.9) | 3.063-150 |
| BDS | 6.3 (8.1) | 2.0 (3.0) | 2.803-150 |
| LF | 8.7 (2.7) (n=11) | 12.2 (3.9) | 2.813-150 |
| DO | 47.1 (25.4) (n=11) | 62.6 (19.9) | 2.17 |
| PR | 17.9 (3.6) (n=11) | 19.6 (2.6) (n=41) | 1.76 |
| SR | 12.9 (2.8) (n=11) | 14.4 (2.8) (n=40) | 1.56 |
| SS | 6.1 (4.1) (n=11) | 7.6 (2.6) (n=41) | 1.18 |
| SWM level 6 between errors | 17.6 (7.3) (n=10) | 13.5 (8.2) (n=41) | 1.45 |
| SWM level 8 between errors | 34.3 (11.7) (n=10) | 30.3 (10.2) (n=40) | 1.10 |
| Duration IPD at falls (y) | 6.50 (4.85) (n=6) | 7.10 (5.22) (n=17) | 0.25 |
| Duration IPD at fluctuation (y) | 7.72 (5.50) (n=9) | 5.77 (5.1) (n=24) | 0.96 |
| Duration IPD at dyskinesia (y) | 5.79 (3.24) (n=7) | 9.14 (5.05) (n=19) | 1.63 |
| No (%) | No (%) | χ2 value | |
| Sex | 6 female | 21 female | 0.006 |
| Loss of balance | 10 (83.3) | 29 (69) | 10.547** |
| Tendency to fall | 5 (41.7) | 21 (50) | 0.033 |
| Fluctuations | 8 (66.7) | 25 (59.5) | 0.013 |
| Dyskinesiae | 7 (58.3) | 21 (50) | 0.033 |
| Levodopa | 13 (76.5) (n=17) | 36 (85.7) | 0.737 |
| Pergolide | 12 (70.6) (n=17) | 15 (35.7) | 5.9293-150 |
| Bromocriptine | 1 (8.3) (n=17) | 4 (9.5) | |
| DA agonist | 13 (76.5) (n=17) | 18 (42.9) | 5.4903-150 |
| Anticholinergics | 2 (16.7) | 9 (21.4) | 0.002 |
| Selegiline | 4 (33.3) | 11 (26.2) | 0.015 |
| Apomorphine | 1 (8.3) | 2 (4.8) | |
| Untreated | 0 | 1 (2.4) | |
↵3-150 P<0.05; **P<0.01.