Clinical characteristics of patients with Parkinson’s disease without orthostatic hypotension (OH), with asymtomatic OH (defined as a systolic blood pressure (SBP) fall ⩾20 mm Hg without postural symptoms) and with symptomatic OH (both a decrease >20 mm Hg in SBP and at least one related symptom)
| Age (y) | % of men | DD (y) | H and Y | ΔSBP (mm Hg) | Levodopa†(mg/day) | Bromocriptine (mg/day) | |
|---|---|---|---|---|---|---|---|
| Without OH (n=38) | 64 (0) | 57.9 | 7 (6) | I:13; II:20 III:5;IV:0 | 9 (6) | 611 (521) | 39 (17) |
| Asymptomatic OH (n=35) | 68 (9) | 57.1 | 7 (6) | I:5; II:20 III:9;IV:11-150 | 30 (9)1-150 | 590 (412) | 42 (19)1-150 |
| Symptomatic OH (n=18) | 67 (9) | 66.7 | 12 (6)1-150 † | I:3;II:9 III:5;IV:11-150 | 46 (17)1-150 † | 1069 (754)1-150 † | 74 (26)1-150 † |
↵1-150 P<0.05 v OH. †P<0.05 v patients with asymptomatic OH.
Values are mean (SD). DD=disease duration; H and Y=Hoehn and Yahr stage; ΔSBP=systolic blood pressure fall when standing; Levodopa=daily dose + dopa-decarboxylase inhibitor.