Table 2

Metabolite ratios of control subjects and patients with multiple sclerosis at basal time

Ins/Cr
(Mean (SEM))
Ins/NAA
(Mean (SEM))
Cho/Cr
(Mean (SEM))
Cho/NAA
(Mean (SEM))
NAA/Cr
(Mean (SEM))
Treated patients83.67 (3.65)2-150 63.15 (2.87)** 92.05 (4.46)68.96 (2.39)2-150 133.39 (4.42)**
WM Lesions86.98 (2.50)** 67.51 (2.84)** 97.79 (3.35)75.39 (2.78)** 130.76 (3.53)**
Untreated patients90.28 (3.28)** 71.87 (4.64)** 103.54 (4.48)81.81 (4.22)** 128.13 (5.63)**
Treated patients75.24 (7.35)49.42 (4.16)97.32 (6.17)64.11 (3.38)151.62 (3.42)
NAWM69.29 (4.81)48.32 (2.49)86.89 (5.52)62.75 (2.81)142.72 (4.38)
Untreated patients63.35 (5.53)47.21 (3.29)82.52 (8.23)61.39 (4.91)133.82 (4.99)2-150
Control subjects68.89 (1.92)44.24 (1.64)86.89 (1.02)55.83 (1.40)156.07 (3.19)
  • 2-150 p < 0.05; ** p < 0.01 v control subjects. WM = white matter; NAWM = normal appearing white matter.