Table 1

Summary of all stroke studies involving the ACE gene

ReferenceSubjects (n)Males/ femalesMean age (y)D/IDDIDIIStudy resultOR
(95% CI)
Sharma et al(1994)6 Cases10055/45 66.80.57/0.43334720Negative1.62
(0.82–3.22)
Controls7333/40 65.40.48/0.52173620
Uedaet al(1995)7 Cases488249/23967.90.54/0.4612727190Negative1.26
(0.84–1.88)
Controls18883/10565.20.50/0.504110542
Markuset al(1995)8 Cases10169/32 64.80.59/0.41364718Positive1.98
(1.11–3.51)
Controls13759/78 63.90.48/0.52307136
Catoet al(1996)9 Cases406195/21174.00.50/0.50114178114Negative0.94
(0.65–1.35)
Controls21591/12472.50.53/0.476310250
Margaglioneet al(1996)10 Cases10151/50 63.60.72/0.28543710Positive1.76
(1.02–3.05)
Controls10957/52 63.60.62/0.38434917
Pullicinoet al(1996)11 Cases60630.61/0.39232710Negative
Controls0
Karioet al(1996)12 Cases13866/72 70.00.47/0.53346341Positive2.44
(1.31–4.55)
Controls10453/51 68.00.34/0.6685541