Table 2

Demographic details and capsaicin cough indices

FeatureAll (n=28,15 F)Normal swallow (n=15, 7F)Abnormal swallow (n=13, 8F)p Value
Age (mean (SD))45.7 (12.0)45.6 (12.3)45.9 (12.1)0.96
BMI (mean (SD))23 (4)24 (4)22 (5)0.21
Swallow speed (% predicted, median (IQR))52 (22–92)99 (60–110)23 (11–37)<0.001
Volume/swallow (% predicted, median (IQR))70 (42–105)106 (72–139)43 (21–58)<0.001
Vital capacity (% predicted, median (IQR))72 (53–91)68 (63–96)75 (46–90)0.63
Max inspiration (mm Hg, median (IQR))58 (42–72)67 (47–89)56 (30–60)0.045
Max expiration (mm Hg, median (IQR))78 (39–98)81 (50–104)70 (22–87)0.29
Capsaicin indices (mean (SD))
 Log conc threshold (mean (SD))−0.296 (0.546)−0.206 (0.565)−0.399 (0.526)0.36
 Log conc 10 coughs/min (mean (SD))0.125 (0.457)0.255 (0.418)−0.026 (0.471)0.12
 Log conc 20 coughs/min (mean (SD))0.409 (0.445)0.550 (0.384)0.245 (0.468)0.07
 Log conc slope (mean (SD))1.041 (0.495)0.994 (0.456)1.095 (0.549)0.61
  • % predicted is adjusted for age and sex. Units of body mass index are kg/m2.