Details of children with arterial stroke in whom inherited prothrombotic abnormalities were identified
| Patient No | Prothrombotic abnormality | Cerebrovascular abnormalities | Other risk factors for stroke | Other family members affected |
|---|---|---|---|---|
| 1 | Type 1 protein S deficiency (low free and total protein S) | Moyamoya | None | Mother |
| 2 | APC resistance; no FVL mutation | None | Familial hypercholesterolaemia | Father and brother |
| 3 | FVL heterozygote | Moyamoya | Noonan syndrome, supravalvular aortic stenosis | Not known |
| 4 | FVL heterozygote | MCA stenosis | None | Not known (father died after stroke) |
| 5 | FVL heterozygote | MCA occlusion | None | Brother |
| 6 | FVL heterozygote | ICA occlusion | None | Not known |
| 7 | FVL heterozygote | None | None | Father |
| 8 | FVL heterozygote | ICA stenosis | None | Not known |
FVL=factor V Leiden mutation; ICA=internal carotid artery; MCA=middle cerebral artery.