Pathogenic MtDNA mutations associated with stroke-like episodes
| Mutation | Gene | Reference |
|---|---|---|
| G1642A | tRNA Valine | Taylor et al 32 |
| A3243G | tRNA Leucine(UUR) | Goto et al 4; Kobayashi et al 15 |
| A3252G | tRNA Leucine(UUR) | Morten et al 29 |
| C3256T | tRNA Leucine(UUR) | Satoet al 35 |
| A3260G | tRNA Leucine(UUR) | Nishino et al 30 |
| T3271C | tRNA Leucine(UUR) | Goto et al 27 |
| T3291C | tRNA Leucine(UUR) | Gotoet al 28 |
| A5814G | tRNA Cysteine | Manfredi et al 33 |
| T9957C | COX III | Manfredi et al 36 |
| A8344G | tRNA Lysine | Hammans et al 37 |
| T7512C | tRNA Serine(UCN) | Nakamura et al 38 |
| T8356C | tRNA Lysine | Zeviani et al 39 |
| Single deletion | Campos et al 34 | |
| Large scale tandem duplication | Poulton et al 40 |