Table 1

Mean (SD) [18F]dopa uptake in healthy volunteers scanned with and without entacapone

Structure (method of analysis)Mean (n=8) without entacaponeMean (n=8) with entacaponeRatio
Mean putamen (Ki)0.0101 (0.0014) min−1 0.0133 (0.0025) min−1 0.76
Mean caudate (Ki)0.0114 (0.0016) min−1 0.0143 (0.0024) min−1 0.80
Mean total striatum (Ki)0.0074 (0.0009) min−1 0.0101 (0.0012) min−1 0.73
Mean putamen (ratio)2.38 (0.25)2.75 (0.39)0.87
Mean caudate (ratio)2.40 (0.21)2.72 (0.27)0.88