Table 2

Epitope selection by pH fractions from isoelectric focusing

Patient 4
Fraction 11 (pH ≈8.8)Fraction 16 (pH ≈8.0)
PPHPPI ×9Clones lost
PASAMI
Fraction 17 (pH ≈7.8)
Fraction 12 (pH ≈8.6)LWWWFS
PPHFPP ×3PWWWFS
PPHLPPPPFPPI
PPHPPPPPFPPN
LALSAS ×2
TAHPPPRPMLVF
AQFNVP
Fraction 13 (pH ≈8.5)
PFHPPP ×2Fraction 18 (pH ≈7.6)
PPTRVAPFHPPP ×4
PPTRVAPAFLPP ×4
PLTRVAFRWPEH ×2
PLTRVR
PLVNVAFraction 19 (pH ≈7.5)
REWHSL ×2PRFLPP ×4
PPWLPL ×2
Fraction 14 (pH ≈8.3)PPFAPR
ELVSVA ×7PQHPPP
ELVRVA ×3PAHQMP
PHFSPP
Fraction 15 (pH ≈8.2)
PLVRVA ×5Fraction 20 (pH ≈7.3)
PLIRVAPAFLPP ×5
PLINVAPFFLPP ×4
PLTCVAPPFQPA
ELIRVA