Clinical characteristics of subject groups (mean (SD))
| Controls (n=10) | CFS (n=10) | MDD (n=10) | |
|---|---|---|---|
| Age (y) | 40.5 (10.4) | 40.5 (9.1) | 38.1 (10.6) |
| Sex ratio (F/M) | 7/3 | 7/3 | 7/3 |
| Weight (kg) | 73.7 (18.8) | 68.0 (14.1) | 70.7 (13.0) |
| NART (full scale IQ) | 113.5 (11.1) | 116.0 (8.9) | 115.6 (7.0) |
| Duration of illness (y) | N/A | 7.1 (4.8) | 5.1 (6.9) |
| Chalder fatigue score | N/A | 27.9 (4.0) | 14.8 (6.9) |
| End tidal CO2 at rest (kPa) | 4.8 (0.5) | 4.8 (0.4) | 4.4 (0.5) |
| HAD (anxiety) | 3.6 (1.8) | 5.5 (1.6) | 11.4 (4.8) |
| HAD (depression) | 0.6 (0.7) | 6.1 (2.0) | 9.1 (5.8) |
| HAD f2-150(excluding Q4) | 0.2 (0.4) | 3.5 (1.7) | 8.2 (5.7) |
| SF36 (scaled scores, (%)): | |||
| Physical functioning | 96.5 (2.4) | 41.5 (21.7) | 81.0 (18.1) |
| Mental health | 85.6 (7.8) | 70.8 (9.6) | 46.4 (24.5) |
| Role physical | 100.0 (0.0) | 20.0 (36.9) | 45.0 (45.3) |
| Bodily pain | 92.8 (12.0) | 54.0 (27.1) | 74.1 (21.7) |
| Role emotional | 96.7 (10.5) | 86.6 (28.3) | 30.0 (39.9) |
| General health | 84.4 (17.6) | 33.2 (14.7) | 45.8 (20.5) |
| Social functioning | 96.3 (8.4) | 41.3 (31.3) | 45.0 (32.4) |
| Vitality | 78.5 (9.1) | 18.0 (10.1) | 32.5 (19.9) |
↵2-150 HAD-f refers to depression subscale score excluding Q4 on fatigue.