Table 4

Abnormal findings on 0.5 and 1.5 tesla MRI in idiopathic Parkinson’s disease (IPD), control, and multiple system atrophy (MSA) patients (average of rater 1 and rater 2)

	IPD	Controls	MSA^4-1	PPV (IPD)^4-152	PPV (IPD+controls)^4-153
0.5 Tesla n (%)		32	29	28
Infratentorial changes:
Infratentorial signal change	0 (0.0)^***	0 (0.0)^**	8.5 (30.4)	100.0	100.0
Any infratentorial abnormality	1.5 (4.7)^***	0 (0.0)^***	18.5 (66.1)	92.5	92.5
BG abnormalities:
Hyperintense rim	0 (0.0)^***	0 (0.0)^**	8.5 (30.4)	100.0	100.0
Isointense rim	6 (18.8)	5 (17.2)	4 (14.3)	40.0	26.7
Relative isointensity putamen/GP	3.5 (10.9)	3.5 (12.1)	7 (25.0)	66.7	50.0
Relative hypointensity putamen/GP	0 (0.0)	0 (0.0)	0.5 (1.8)	100.0	100.0
Absolute hyperintensity of putamen	0 (0.0)^**	0 (0.0)^**	6.5 (23.2)	100.0	100.0
Absolute hypointensity of putamen	7 (21.9)	11 (39.7)	13 (46.4)	65.0	41.9
Putaminal atrophy	0 (0.0)^4-150	0 (0.0)	4.5 (16.1)	100.0	100.0
1.5 Tesla n (%)	15	16	16
Infratentorial changes:
Infratentorial signal change	0 (0.0)^**	0.5 (3.1)^4-150	6.5 (40.6)	100.0	92.9
Any infratentorial abnormality	1 (6.7)^***	1.5 (9.4)^***	11.5 (71.9)	92.0	82.1
BG abnormalities:
Hyperintense rim	0 (0.0)^**	0 (0.0)^**	6.5 (40.6)	100.0	100.0
Isointense rim	4 (26.7)^†	10.5 (71.9)	7.5 (46.9)	65.2	34.1
Relative isointensity putamen/GP	12 (80.0)	8.5 (53.1)	11 (68.8)	47.8	34.9
Relative hypointensity putamen/GP	1 (6.7)	0.5 (3.1)	4.5 (28.1)	81.8	75.0
Absolute hyperintensity of putamen	0 (0.0)	0 (0.0)	0.5 (3.1)	100.0	100.0
Absolute hypointensity of putamen	14 (93.3)	15 (93.8)	15 (93.8)	51.7	34.1
Putaminal atrophy	0 (0.0)	0 (0.0)	2.5 (15.6)	100.0	100.0

↵4-150 p<0.05, ^**p<0.01, ^***p<0.001 less often than in MSA patients; ^†p<0.05 less often than in controls.
↵4-152 v IPD.
↵4-153 v IPD and controls.
↵4-1 =sensitivity, PPV=positive predictive value; BG = basal ganglia.