No | Age | Plaques | Tangles | AD | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cingulate | HC | Frontal | Occipital | Parietal | Cingulate | HC | Frontal | Occipital | Parietal | ||||
12 | 44 | O | O | O | O | O | O | O | O | O | O | ||
13 | 56 | XX | XXX | XXX | XXX | XX | O | XXX | O | O | O | Probable | |
15 | 65 | O | O | O | O | O | O | XX | O | O | O | ||
17 | 71 | O | XX | X | X | XX | O | X | O | O | O | Possible | |
18 | 76 | O | O | O | O | O | O | X | O | O | O | ||
19 | 83 | XXX | XXX | XXX | XX | XXX | X | XXX | X | O | X | Probable | |
25 | 87 | XX | XX | XXX | XX | XX | X | X |
Blocks were taken from the cortical regions indicated (HC=hippocampus) and examined immunocytochemically for plaques and tangles. Two cases were considered to be probably AD (column headed AD). Semiquantitative assessment of plaques and tangles: O= absent; X=sparse; XX=moderate; XXX=severe.