Table 1

Basic demographic data and clinical features of patients with MND

PatientAgeSexEducation (years)Symptom duration (months)Symptom onsetLimb UMNLimb LMNBulbar UMNBulbar LMNBulbar score
148M105L+++0
272F1024B++++5 m
366F913B+++5 m
475M918B++++3
564M137B++++2
652M1020B+++5 m
744M105B+++6 m
875F913B++4 m
962M113L+++4
1074F910B+++4
1170F913B++3
1254F1317L+++2
1375M926L+++2
1465M912B+++5
1581M96B+++2
1681F911B+++5
1778F919B+++5
1875M1014B+++5
  • Disease duration = time from first symptoms to testing date.

  • Symptom onset: B = bulbar onset; L = limb-onset.

  • Examination findings: UMN = upper motor neuron signs; LMN = lower motor neuron signs; (+) = present; Bulbar score = dysphagia score (0–3) + dysarthria score (0–3) (see text); m=mute.