Clinical features of patients with MRI defined subgroups of hippocampal sclerosis and normal MRI
| Unilateral focal | Unilateral diffuse | Bilateral | Normal MRI | |
|---|---|---|---|---|
| Number of patients | 6 | 16 | 6 | 2 |
| Age (y, median (range)) | 37.5 (30–42) | 33.5 (19–49) | 33 (27–44) | 41 (34–48) |
| Duration of epilepsy (y, median (range)) | 22 (10–39) | 21 (6–40) | 29 (18–42) | 14.5 (11–18) |
| Age of onset of epilespy (y, median (range))2-150 | 14 (2–23) | 7.5 (1–24) | 2.5 (2–13) | 26.5(16–37) |
| Number (%) of patients with: | ||||
| Febrile convulsions | 2 (33) | 7 (44) | 3 (50) | 0 |
| Meningitis/encephalitis | 0 | 5 (31)† | 0 | 0 |
| > 10 SGS/lifetime | 2 (33) | 8 (50) | 6 (100)‡ | 1 |
| CPS/month (median) | 4 | 13 | 5 | 11 |
↵2-150 p=0.05; †p=0.04; ‡p=0.02.
The age of onset differed significantly between groups of patients with temporal lobe epilepsy and different categories of hippocampal sclerosis. SGS=secondarily generalised seizures, CPS=complex partial seizures.