Comparison between scores at baseline and after levodopa on UPDRS (part III), BPRS, total HAM-D, and categories I, II, and III of HAM-D in IPD and MSA patient groups
| Baseline | 90 min after levodopa | p Value | |
|---|---|---|---|
| Patients with IPD: | |||
| UPDRS | 34.5 (14.8) | 13.2 (6.2) | 0.0001 |
| BPRS | 18.9 (6.8) | 15.5 (5.1) | 0.005 |
| HAM-D | 14.9 (6.8) | 6.8 (4.9) | 0.002 |
| Category I | 3.4 (2.1) | 1.4 (2.0) | 0.005 |
| Category II | 1.3 (1.1) | 0.4 (0.5) | 0.014 |
| Category III | 3.9 (2.6) | 1.1 (1.6) | 0.0001 |
| Patients with MSA: | |||
| UPDRS | 45.3 (12.3) | 34.2 (11.6) | 0.0001 |
| BPRS | 17.1 (1.1) | 16.9 (1.4) | 0.19 |
| HAM-D | 6.1 (4.3) | 5.1 (4.3) | 0.04 |
| Category I | 1.8 (1.2) | 1.0 (1.1) | 0.01 |
| Category II | 1.4 (0.7) | 1.3 (0.6) | 0.40 |
| Category III | 0.4 (1.2) | 0.3 (1.1) | 0.40 |
Category I (items 1, 2, 3): mood depression, guilt, suicide; category II (items 7, 8): work and interests, retardation; category III (items 9, 10, 11): agitation, anxiety psychic, anxiety somatic symptoms.