Demographics of study group
| Characteristics | Corticobasal degeneration (n=15) | Progressive supranuclear palsy (n=34) | Healthy controls (n=25) |
|---|---|---|---|
| Age (y) | 67.9 (2) | 66.6 (1.2) | 70 (0.8) |
| Sex | 8 M / 7 F | 23 M / 11 F | 14 M / 11 F |
| Education (y) | 14.3 (0.8) | 14.4 (0.5) | 13.2 (0.4) |
| Duration (months) | 46.5 (5.7) | 52 (4.5) | — |
| Mini mental state examination score | 26.1 (1.2) | 26 (0.8)1-150 | 28.6 (0.3) |
| Total Mattis dementia rating scale score† | 120.5 (4.2) | 118.6 (2.4) | — |
| Total UPDRS motor scores | 26.2 (2)1-150 | 21.2 (1.3) | — |
Data are presented as mean (SEM). UPDRS=unified Parkinson’s disease rating scale score; UPDRS maximum score was 54, and included only motor evaluation of axial and most affected limb (bradykinesia, rigidity, tremor, or dystonia).
↵1-150 Patients with progressive supranuclear palsy had a significantly lower (worse) mini mental state examination score than controls (ANOVA, p<0.05), patients with corticobasal degeneration had a higher (worse) total motor score than those with progressive supranuclear palsy (p<0.05). The score of normal controls, not tested in this study with the Mattis dementia rating scale score, is ⩾136. †This analysis included 12 patients with corticobasal degeneration and 28 with progressive supranuclear palsy.