Mean (SD) normalised volumes (ml) for control subjects and all patients and mean (SD) volume changes2-151(ml and %) for all patients
| Control | All | p Value | Volume change2-151 | |
|---|---|---|---|---|
| Brain stem | 28.1 (2.4) | 22.3 (3.1) | <0.0001** | −5.8 (3.1) −20.6% |
| Cerebellum | 147.8 (11.0) | 120.1 (13.7) | 0.0001** | −27.6 (13.7) −18.7% |
| Upper cervical cord | 4.4 (0.68) | 2.4 (0.68) | <0.0001** | −2.1 (0.68) −46.4% |
| Cerebral grey matter | 590.3 (47.2) | 590.8 (53.5) | NS | +0.5 (53.5) +0.1% |
| Cerebral white matter | 465.5 (44.0) | 409.9 (47.1) | 0.0007** | −55.6 (47.1) −11.9% |
| Cerebral hemispheres | 1055.8 (80.9) | 1000.1 (65.0) | 0.047* | −56.0 (65.0) −5.3% |
| Ventricles | 14.8 (10.0) | 17.9 (11.3) | NS | +3.2 (11.3) +21.3% |
| Corpus callosum‡ | 6.4 (1.4) | 5.1 (1.0) | 0.004** | −1.4 (1.0) −21.4% |
↵2-151 Mean of (individual patient volume - mean control volume);‡Corpus callosal area in cm2; *Trend (0.006<p<0.05); **significant after Bonferroni (p<0.006).