Mean (SD) normalised volumes (ml) and mean (SD) volume changes3-151(ml and %) of RR and SP patients
| RR | SP | p(1) | RR volume change‡ | SP volume change‡ | p Value (2) | |
|---|---|---|---|---|---|---|
| Brain stem | 22.6 (2.9) | 21.9 (3.3) | NS | −5.4 (2.9) −19.3% | −6.1 (3.3) −21.8% | NS |
| Cerebellum | 123.6 (2.9) | 116.7 (11.1) | NS | −24.2 (15.4) −16.4% | −31.1 (11.1) −21.0% | NS |
| Upper cervical cord | 2.6 (0.68) | 2.1 (0.59) | 0.01* | −1.8 (0.68) −40.8% | −2.3 (0.59) −52.0% | 0.01* |
| Cerebral grey matter | 582.0 (39.1) | 599.7 (64.7) | NS | −8.3 (39.1) −1.4% | +9.4 (64.7) +1.6% | NS |
| Cerebral white matter | 429.5 (45.1) | 390.4 (41.4) | 0.007* | −36.0 (45.1) −7.7% | −75.2 (41.4) −16.2% | 0.008* |
| Cerebral hemispheres | 1010.2 (58.7) | 990.0 (70.9) | NS | −45.6 (58.7) −4.3% | −65.9 (70.9) −6.2% | NS |
| Ventricles | 16.1 (13.2) | 19.8 (9.0) | NS | +1.3 (13.2) +8.8% | +5.0 (9.0) +33.8% | NS |
| Corpus callosum‡ | 5.3 (1.1) | 4.8 (1.0) | NS | −1.1 (1.1) −17.4% | −1.6 (1.0) −25.5% | NS |
↵3-151 Mean of (individual patient volume-mean control volume);‡Corpus callosal area in cm2; p(1)=Comparison of normalised volumes for RR and SP; p Value (2)=comparison of volume changes for RR and SP; *Trend (0.006<p< 0.05); **significant after Bonferroni (p<0.006).