Distribution of the intronic polymorphism in the presenilin-1 gene
| Genotype1-150 | Allele1-151 | ||||||
|---|---|---|---|---|---|---|---|
| 1/1 | 1/2 | 2/2 | 1 | 2 | |||
| Younger control | 21 (0.36) | 30 (0.51) | 8 (0.14) | 0.61 | 0.39 | ||
| ApoE ε4 non-carriers | 14 (0.33) | 22 (0.51) | 7 (0.16) | 0.58 | 0.42 | ||
| ApoE ε4 carriers | 7 (0.44) | 8 (0.50) | 1 (0.06) | 0.68 | 0.32 | ||
| Early-onset AD | 21 (0.36) | 30 (0.51) | 8 (0.14) | 0.61 | 0.39 | ||
| ApoE ε4 non-carriers | 9 (0.36) | 13 (0.52) | 3 (0.12) | 0.62 | 0.38 | ||
| ApoE ε4 carriers | 12 (0.35) | 17 (0.50) | 5 (0.15) | 0.62 | 0.38 | ||
| Elderly control | 59 (0.37) | 80 (0.51) | 19 (0.12) | 0.63 | 0.37 | ||
| ApoE ε4 non-carriers | 50 (0.39) | 61 (0.48) | 17 (0.13) | 0.63 | 0.37 | ||
| ApoE ε4 carriers | 9 (0.30) | 19 (0.63) | 2 (0.07) | 0.62 | 0.38 | ||
| Late-onset AD | 61 (0.39) | 76 (0.48) | 21 (0.13) | 0.63 | 0.37 | ||
| ApoE ε4 non-carriers | 26 (0.38) | 34 (0.49) | 9 (0.13) | 0.62 | 0.38 | ||
| ApoE ε4 carriers | 35 (0.39) | 42 (0.47) | 12 (0.13) | 0.63 | 0.38 | ||