Table 5

Comparison of the results obtained in four studies using the same simulation approach in computing the statistical power for a parallel group design with follow up duration of 6 months and for expected treatment effects of 60% and 70%. The response variable studied was the number of new enhancing lesions

Sample sizeTruyen
et al7 (n=12)
Nauta
et al6 (n=23)
Tubridy
et al8 (n=31)
Present study (n=65)
2×10 60---35
7084716157
2×206080706350
7093888174
2×306089787262
7099958985
2×406094878374
70991009592