Regional CMRO₂ (ml/min/dl) values for cases 1 and 2 compared with a group of normal controls (mean age ( SD) 69.3 (8.6); n=9)

Brain region	Normal mean( SD)	Case 1	Case 2
Left cingulate gyrus	3.22 (0.52)	2.08^*	1.94^*
Right cingulate gyrus	3.33 (0.68)	1.93^*	2.05
Left F1	2.92 (0.27)	2.25^*	1.92^*
Right F1	2.96 (0.36)	2.17^*	1.75^*
Left F2	2.71 (0.31)	2.20	1.95^*
Right F2	2.66 (0.36)	2.09	2.07
Left F3	2.67 (0.37)	2.21	1.97
Right F3	2.73 (0.39)	2.14	2.20
Left anterior temporal	2.74 (0.40)	2.60	2.26
Right anterior temporal	2.76 (0.41)	2.75	2.56
Left posterior temporal	2.78 (0.42)	2.22	2.34
Right posterior temporal	2.79 (0.42)	2.22	2.18
Left anterior parietal	2.84 (0.42)	2.74	2.28
Right anterior parietal	2.84 (0.42)	2.81	2.45
Left posterior parietal	2.85 (0.40)	2.30	2.19
Right posterior parietal	2.86 (0.41)	2.18	2.21
Left caudate	3.55 (0.63)	3.42	3.05
Right caudate	3.58 (0.62)	3.28	3.16
Left putamen	3.52 (0.66)	3.85	3.28
Right putamen	3.54 (0.65)	3.77	3.67
Left thalamus	3.47 (0.58)	3.00	3.15
Right thalamus	3.49 (0.61)	3.12	3.47
Left occipital	3.49 (0.62)	2.98	3.01
Right occipital	3.48 (0.61)	2.87	2.99
Left cerebellum	3.72 (0.43)	3.41	3.42
Right cerebellum	3.64 (0.55	3.22	3.12

F1 = anterior frontal gyrus; F2 = middle frontal gyrus. F3 = posterior frontal gyrus; T1 = superior temporal gyrus; T2 = middle temporal gyrus; T3 = inferior temporal gyrus; P1 = post central gyrus, P2 = inferior parietal lobe. ^*Indicates values which are outside two SD of the normal values (outside 95% confidence interval).