Patient No | Age | Sex | Disease | Main symptoms | Location of electrodes | Minimum stimulation to suppress symptoms | UPDRS (total score) (before/after stimulation) |
1 | 46 | F | Parkinson's disease | Rigidity | L GPi | 2.5 V, 120 Hz | 17/5 |
2 | 58 | F | Parkinson's disease | Tremor | L VIM | 3.0 V, 100 Hz | 39/14 |
3 | 66 | F | Parkinson's disease | Tremor | R VIM | 1.0 V, 120 Hz | 24/7 |
4 | 53 | M | Parkinson's disease | Tremor, rigidity | R VIM | 2.0 V, 120 Hz | 39/23 |
5 | 51 | M | Parkinson's disease | Akinesia, rigidity | Bil GPi | 1.0 V, 120 Hz | 43/24 |
TRS | |||||||
6 | 63 | M | Essential tremor | Tremor | L VIM | 1.3 V, 120 Hz | 3/0 |
VIM=thalamic nucleus ventralis intermedius; GPi =globus pallidus internus; UPDRS=unified Parkinson's disease rating scale; TRS=tremor rating scale; L=left; R=right; Bil=bilateral. Stimulus duration was fixed at 200 μs. The values in the table were obtained during NIRS measurements.