Persistent improvements in long term (1 year follow up) reports of pallidotomy
| Author (year) | Maximal follow up (months)/n | Dyskinesia | UPDRS score in off | Bradykinesia | Tremor | Time in off | Gait/stability in off | On period features other than dyskinesia | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Contralateral | Ipsilateral | Motor part | ADL | Contralateral Ipsilateral | |||||||||||||||||
| This series (1998) | 14/20 | + | (+) | + | + | (+) | − | + | − | + | − | ||||||||||
| Dogali et al; Fazziniet al (1995, 1997) 1 6 | 12 /18, 24/11 | + | ? | + | + | + | + | (+) | ? | + | Motor and ADL score, gait, bradykinesia, mild, but persistent, ?>1year | ||||||||||
| 36/10, 48/5 | (+/−) at 4 years | ?>1 year | ?>1 year | ||||||||||||||||||
| Baronet al (1996)17 | 12 /15 | + | ? | + | (+) | + | + | + | (+/−) | (+/−) | |||||||||||
| Kishore et al(1997)16 | 12/11 | (+) | (+) | + | + | + | (+/−) | + | ? | + | − | ||||||||||
| (6 months) | (6 months) | (6 months) | (6 months) | ||||||||||||||||||
| Langet al; Kumar et al (1997, 1998)8 12 | 12 /27 | + | (+/−) | + | + | + | (+/−) | (+/−) | ? | (+/−) | (+/−) | ||||||||||
| 24/11 | (after 1 year) | (after 3 months) | (small n) | (after 3–6 months) | (after 1 year) | ||||||||||||||||
| Johansson et al(1997)7 | 12/? | + | + | − | − | − | − | + | − | − | − | ||||||||||
n=Number of patients; improvement rated as +=persistent; (+)=persistent, but decreasing; (+/−)=lost or decreased; −=not improved; ?=not reported; bold=consistently improved in most reports