Changes in cognitive status in participants without dementia at baseline after a median follow up of 4 years, stratified for the MTHFR genotypes and sex
| MTHFR genotype | Women (n=121) | Men (n=51) | |||||
|---|---|---|---|---|---|---|---|
| ala/ala | ala/val | val/val | ala/ala | ala/val | val/val | ||
| Number | 59 | 51 | 11 | 28 | 21 | 2 | |
| Median MMSE follow up | 24 | 25 | 27 | 26 | 26 | 23.5 | |
| IQR | 19–27 | 19–28 | 25–29 | 19.5–28 | 24–27.5 | — | |
| Median decline of MMSE | 4 | 4 | 2 | 2 | 3 | 4.5 | |
| IQR | 2–8 | 1–9 | 0–4 | 1–5.8 | 2–4.5 | — | |
| Diagnosis of dementia (yes/no)2-151 | 18/36 | 13/35 | 0/11 | 5/20 | 1/18 | 0/2 | |
2-150 IQR=interquartile ranges, representing the 25% and 75% percentiles of the distribution.
↵2-151 Total number of participants to the psychiatric interview was 113 women and 46 men.