T1 and T2 lesion loads, average lesion MTR and brain volumes from patients with multiple sclerosis with and without cognitive impairment
| Unimpaired | Impaired | p Value* | |
| Median T2 lesion load (range) (ml) | 8.4 (2.4–18.4) | 38.4 (4.7–73.6) | 0.002 |
| Median T1 lesion load (range) (ml) | 1.4 (0.1–6.2) | 6.7 (1.2–47.2) | 0.01 |
| T1/T2 ratio | 0.12 (0.03–0.34) | 0.38 (0.06–0.71) | 0.03 |
| Average lesion MTR (SD) (%) | 35.1 (2.0) | 32.1 (3.0) | 0.006 |
For statistical analysis, see text.