Table 2

Clinical features associated with significantly impaired quality of life scores

Mean PDQ-39 summary index scores
Feature present
(SD)
Feature not present (SD)p Value
Depression (BDI>17); n=1839 (18.3)16.7 (11.2)<0.001
MMSE<25; n=1349.4 (19.2)24.4 (15.9)<0.001
History of hallucinations2-150; n=1539 (16.2)27.2 (19)0.0262-151
History of falls2-150; n=5836.2 (18.4)21.4 (17.1)<0.001
Postural instability; n=4333.7 (19.3)18.7 (11.8)<0.001
Gait impairment2-150; n=6135.6 (19.1)20 (15)<0.001
Akinetic-rigid subtype; n=6820.7 (2.8)14.6 (3.3)2-152 0.005
  • 2-150 Patient report on interview;

  • 2-151 only marginally significant;

  • 2-152 tremor dominant subtype; BDI=Beck depression inventory score; MMSE=mini mental state examination score.