Summary of studies investigating the relation between the OCSP clinical classification of ischaemic stroke and the site of any lesion on CT or MRI
Author | Number of ischaemic strokes | Recent infarcts on CT or MRI (%) | Proportion of infarcts appropriate to each of the syndromes(%) | Comments | |||||
---|---|---|---|---|---|---|---|---|---|
TAC1 | PAC1 | LAC1 | POC1 | Overall | |||||
Anderson et al19944 | 248 | 162 (65) | 46/58 (79) | 25/44 (57) | 30/48 (62) | 12/20 (60) | 113/162 (70) | Community first ever strokes, retrospectively classified | |
Lindgrenet al 19945 (and personal communication) | 179 | 110 (61) | 35/39 (90) | 21/37 (57) | 13/22 (59) | 12/12 (100) | 81/110 (74) | First ever stroke. Previously unpublished data | |
Wardlaw et al 19966 | 108 | 91(84) | 30/33 (91) | 30/36 (83) | 12/14 (86) | 8/8 (100) | 80/91 (88) | Hospital series. Included previous non-disabling strokes | |
Mead et al 19967 | 195 | 158 (81) | 41/46 (89) | 48/57 (84) | 25/37 (68) | 16/18 (89) | 130/158 (82) | Hospital series. Only half of CT reports of 378 patients with ischaemic stroke were available | |
Al-Buhairi et al19988 | 378 | 239 (63) | 40/49 (82) | 79/82 (94) | 65/66 (98) | 32/32 (100) | 216/228 (95) | Hospitals series of acute ischaemic strokes. Included previous strokes | |
Current study | 1012 | 655 (65) | 69/87 (79) | 213/298 (71) | 104/144 (73) | 105/126 (83) | 492/655 (76) | Validity similar for those with and without previous strokes |
“Appropriate infarcts” are defined in different ways.
For Anderson et al, Meadet al, and Lindgren et al, 4 5 7 any cortical infarct or large subcortical infarct is defined as “appropriate” for both TACIs and PACIs, small subcortical for LACIs and posterior circulation for POCIs.
Wardlaw et al 6 and the current study used stricter definitions of “appropriate infarcts”: large cortical, medium cortical, and large subcortical were appropriate for TACIs; and medium cortical, small cortical, and large subcortical were appropriate for PACIs.
Al-Buhairi et al 8 classified complete MCA territory infarction, ACA territory infarction as appropriate for TACIs, partial MCA infarcts, and subcortical infarcts as appropriate for PACIs.