Parameter | % of Prepal scores at | p Values | |||||
---|---|---|---|---|---|---|---|
2 y | 3 y | Prepal v 2 y | Prepal v 3 y | 2 y v 3 y | |||
Dyskinesias (on): | |||||||
CL | 16 | 19 | 0.001 | 0.003 | NS | ||
IPS | 88 | 99 | NS | NS | NS | ||
AX | 67 | 67 | NS | NS | NS | ||
TOT | 61 | 78 | 0.017 | NS | NS | ||
Resting tremor (off): | |||||||
CL | 13 | 38 | 0.003 | 0.019 | NS | ||
IPS | 69 | 109 | NS | NS | NS | ||
Limb brady (off): | |||||||
CL | 91 | 117 | NS | NS | 0.015 | ||
IPS | 105 | 144 | NS | 0.001 | 0.001 | ||
Limb brady (on): | |||||||
CL | 98 | 113 | NS | NS | NS | ||
IPS | 115 | 140 | NS | 0.026 | NS | ||
Modified Hoehn and Yahr stage (off) | 108 | 120 | NS | NS | NS |
Prepal=Prepallidotomy; CL=contralateral; IPS=ipsilateral; AX=axial; TOT=total; brady=bradykinesia. Increases in percentage imply worsening.
p Values apply to the mean values of measurements, and are adjusted for multiple comparisons (see Methods).