Changes in ADLs and other parameters
| Parameter | % Of prepal scores at | p Values | ||||||
|---|---|---|---|---|---|---|---|---|
| 6 months | 2 y | 3 y | Prepal v 2 y | Prepal v 3 y | 6 months v 2 y | 6 months v 3 y | ||
| ADL (off) | 67 | 109 | 123 | NS | NS | <0.001 | <0.001 | |
| ADL (on) | 57 | 169 | 194 | 0.010 | 0.019 | <0.001 | <0.001 | |
| Compl-dyskinesia | 23 | 92 | 100 | NS | NS | 0.008 | 0.005 | |
| Compl-fluctuation | 76 | 89 | 89 | NS | NS | NS | NS | |
| Mentation, behaviour, and mood | 43 | 107 | 174 | NS | NS | NS | 0.009 | |
Prepal=Prepallidotomy; ADL=activities of daily living; CL=contralateral; IPS=ipsilateral; ADL=activities of daily living; Compl=complications.
Prepal v 6 months: ADL-off p=0.014 (improved); rest are NS; 2 y v 3 y: NS.
Increase in percentage implies worsening.
p Values apply to the mean values of measurements, and are adjusted for multiple comparisons (see Methods).