Table 2

Clinical characteristics of patients with recurrent childhood tics

Patient Sex Age of onset Description of tics Distribution of tics Childhood tics Family history Associated psychiatric symptoms Medication trials Course Duration of follow up (y)
14M25Phonations and multiple motor ticslarynx, face, neck, limbsMultiple motor ticsTicsOCDNo benefit from DZP, ALPZ, PMZWaxing and waning, improved20
15M31Multiple motor ticsFace, neckUnspecifiedImprovement on CLNZ, FLUOX, VPAWaxing and waning, improved11
16M32Multiple motor ticsFace, neckEar wigglingOCDNo benefit from CLNZWaxing and waning, improved8
17M41Multiple motor ticsFaceBlinking and mannerismsOCDOCD and anxiety disorderUntreatedWaxing and waning16
18F28Multiple motor ticsFace, neckBlinkingTicsOCDImprovement on CLNZRelapsing-remitting20
19M61Throat clearing phonation and multiple motor ticsFace, larynx, neckUnspecifiedTicsOCDNo benefit on TRHX, improvement on CLNZStable13
20F62Jaw opening tic, abdominal tensing ticFace, abdomenBlinkingNo benefit from TRHX, BACStable10
21M63Multiple phonations, facial ticsNeck, face, abdomenFacial grimacingTicsNo benefit from CLNZ, CLON, HALStable17
22F29Single tongue thrusting ticTongueBlinkingUntreatedStable12
  • ALPZ=alprazolam; BAC=baclofen; CLNZ=clonazepam; CLON=clonidine; DZP=diazepam; FLUOX=fluoxetine; HAL= haloperidol; OCD=obsessive compulsive disorder; PMZ=pimozide; TRHX=trihexiphenidyl; VPA=valproate.