Table 2

QoL scores compared between groups of patients identified by the presence or absence of clinical features or complications that significantly impair quality of life

		EQ-5D SI				EQ-5D VAS			PD39 SI			SF36 Physical summary score		SF36 Mental summary score
		(mean)	p Value			(mean)	p Value		(mean)	p Value		(mean)	p Value	(mean)	p Value
Depression (BDI±9):
Present	0.4	<0.0001		54.9	<0.0001		39.0	<0.0001	31.3	0.0001	43.6	<0.0001
Absent	0.7			76.7			16.7		40.3		52.0
Mini mental score <25:
Present	0.2	<0.0001		51.1	0.007		49.4	<0.0001	29.7	0.05	40.9	0.006
Absent	0.7			69.0			24.4		37.2		49.5
Falls:^2-150
Present	0.4	<0.0001		58.6	0.006		36.2	<0.0001	31.4	0.006	46.2	0.3
Absent	0.8			71.7			21.4		39.8		48.5
Postural instability:
Present	0.4	<0.0001		57.2	<0.0001		33.7	0.001	32.2	0.0007	47.8	0.7
Absent	0.8			77.6			18.7		42.3		46.3
Change in health over the previous year:^2-150
Improvement^2-151	0.6	0.7		70.5	0.9		16.8	0.2	36.2	0.8	53.4	0.2
No change^2-152	0.6	<0.0001		70.9	<0.0001		25.1	0.0001	37.0	0.003	48.0	0.1
Worsening^2-153	0.3	0.0002		49.1	0.0001		43.4	0.0002	30.0	0.01	43.3	0.1
Hoehn and Yahr stage:^2-153
I	0.9			78.5			16.6		46.2		49.5
II	0.6			66.8			28.1		35.5		48.5
III	0.3			53.8			40.8		28.2		43.9
IV/V	0.2	0.0001		52.0	0.02		38.6	0.0001	22.0	0.005	35.3	0.05

VAS=Visual analogue scale; SI=summary index;
↵2-150 self reported;
↵2-151 improvement compared with no change,
↵2-152 no change compared with worsening,
↵2-153 Kruskall -Wallis test for all three/four levels; all other comparisons were Mann-Whitney tests